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Lytera® 2.0 Pigment Brightening Serum by SkinMedica®

$170.00 CAD

In stock

Useful with:

Even Up® Clinical Pigment Perfector® SPF 50 by Colorescience® (Tinted)

Select optional add-ons and then click "Add to Cart".


  • Morning and evening, before moisturizer.
  • Face, neck, chest or as needed.

Best for:

  • Redness, dark spots, discolouration.
  • All skin types.

If you have dark spots, pigmentation or dull-looking skin, this is the skincare product for you. It can be an alternative to prescriptions or hydroquinone-based products you may have already tried. But, it’s suitable for all skin types – so anyone can use it.

In a study, 79% of participants said they had more evenly-toned skin after 12 weeks of using this product. 85% said they had better skin, overall.

Hyperpigmentation can be caused by genetics and sun damage. When combined together, these factors can create a difficult problem to treat, especially for South Asian, African American, Hispanic or other ethnicities with commonly coloured skin types. We explain the science behind skin pigmentation problems, here. Examples of this condition include:

  • Macular (flat and dark) acne scars
  • Brown spots, also known as sun spots, liver spots, age spots or blotchy-ness
  • Freckles
  • Melasma, also known as ‘the mask of pregnancy’

And even more types of photodamage, which we list here.

Traditionally, prescription-based hydroquinone has been used to lighten dark spots. Hydroquinone is not found to be dangerous, but it has raised concerns among patients. Those with sensitive skin can experience dryness or redness from it. Plus, it shouldn’t be used long-term, regardless. Lytera 2.0 provides a good alternative as a hydroquinone-free pigment corrector.

Another ingredient that has been shown to regulate the production of melanin in the skin, and to help with discolouration, is niacinamide (vitamin B3). Lately, niacinamide has become a popular go-to ingredient for many seeking to even their skin tone.

Lytera 2.0 goes beyond just being a niacinamide treatment. It includes several other ingredients which, together, have been clinically studied to reduce hyperpigmentation in as little as three months.

Note: You may also be interested in the Even Up® Clinical Pigment Perfector® Sunscreen by Colorescience®, which we also carry. See a link to its clinical study, and more details, here. Both Lytera® 2.0 and Even Up® Clinical Pigment Perfector® are suitable for pigmentation issues, but the latter also comes with built-in sun protection. Lytera® 2.0 is meant to work on healing the pigments themselves, whereas Even Up® also works to cover up pigments. For best results, we may recommend you use both treatments, and not just one.

A few helpful things to know about this product:

To be truly effective, this product must be used with a high-quality, high-grade, broad-spectrum SPF. We have great options for this at our clinic, including some by SkinMedica®. Shop our sunscreens, here.

This product is also recommended to enhance other skin pigmentation procedures, such as chemical peels or laser treatments. Patients can also see better results when it is combined with other topical skin care products, in a regular routine. If you are experiencing melasma, or would otherwise like to solve your pigmentation issues, we encourage you to book a consultation at our clinic, for a more comprehensive treatment plan.

See also: 

Notable skin care ingredients:

Niacinamide – this ingredient is widely and popularly used in many skin care products aiming to treat hyperpigmentation today. It is vitamin B3. It regulates both melanin and oil production, and is an antioxidant, too.

Tetrapeptide-30 – a peptide (collagen precursor) that is known to support skin tone by blocking the process of discolouration in the skin.

Tranexamic acid – this ingredient is used to safely fade dark spots and discolouration by inhibiting melanin production in the skin. It is also anti-inflammatory. It was originally used to prevent blood loss.

Phenylethyl resorcinol – an antioxidant and skin lightening ingredient. It is found in Scotch pine bark. Some claim it is more effective than kojic acid, when it comes to prevention of discolouration.

Phytic acid – an antioxidant preventing UV damage which is used for treating discolouration in skin care. It is also a very mild exfoliant.

Plankton extract – a marine-based ingredient taken from algae, seaweed and other sources. It can help with moisture retention.

Alteromonas ferment extract – also taken from the benefits of the seas, this is a soothing, water-binding ingredient, to hold moisture in the skin.

Tocopheryl acetate – a synthetic form of Vitamin E, acting as an antioxidant.

Plus other plant extracts, antioxidants and moisturizing ingredients.

Before & afters gallery showing results of studies using Lytera® 2.0 Pigment Brightening Serum

Click on a thumbnail to open up a gallery, and see larger versions of the images.

Weight / Size

60 mL


Water/Aqua/Eau, Butylene Glycol, Glycerin, Niacinamide, Polyacrylate-13, Phenylethyl Resorcinol, Tranexamic Acid, Vitis Vinifera (Grape) Flower Cell Extract, Plankton Extract, Tetrapeptide-30, Artemisia Capillaris Flower Extract, Vibrio Alginolyticus Ferment Filtrate, Alteromonas Ferment Extract, Tocopheryl Acetate, Polyisobutene, Polysorbate 20, Caprylic/Capric Triglyceride, Hydroxyacetophenone, Phytic Acid, Diethylhexyl Syringylidenemalonate, Disodium EDTA, Ethylhexylglycerin, Phenoxyethanol

Shipping & pickup options

  • Free store pickup: ready within 24 hours when we're open. 13805 104th Avenue, Suite #101 Surrey, BC. View our location on Google Maps. We will e-mail or call when ready.
  • Free shipping: eligible on orders over $200 in B.C., over $500 for the rest of Canada and the U.S.A. (before applicable taxes).
  • Flat rate shipping: $15 within B.C., $20 for the rest of Canada and the U.S.A.
  • All prices in CAD.
  • Shipping times estimated to arrive within 5 - 9 days. May be delayed due to Covid-19.


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